What is Halaven 0.44 mg/ml Injection ? Halaven is an injectable medicine that contains “Eribulin mesylate” as an active ingredient. This medication is classified as a “non-taxane microtubule inhibitor”. Halaven cancer medicine should only be administered under the supervision of a qualified physician experienced in the appropriate use of cytotoxic medicinal products. When is Halaven 0.44 mg/ml Injection prescribed ? Halaven (Eribulin) is a chemotherapy medicine, used for the treatment of patients with locally advanced or metastatic breast cancer. How Does Halaven (Eribulin) Injection Work ? Eribulin mesylate works by disrupting the microtubular network in cells that is essential for cell division. It inhibits the growth of microtubules into the “mitotic spindle,” which is the apparatus that is responsible for physically separating the molecules of the cells. Without this essential structure, cancer cells can no longer grow and thus die. What are the adverse effects of Halaven 0.44 mg/ml Injection ? Side effects are unwanted effects of a medicine. Halaven may cause some serious, life-threatening side-effects. Side effects can range from mild to severe and the risk of getting those varies from person to person. The following are some of the side effects that may occur from those medicines that contain Eribulin : Common Side Effects of Halaven Injection : Low white blood cell count (neutropenia) ; Nausea ; Low red blood cell count (anemia) ; Constipation ; Weakness or tiredness ; Hair loss (alopecia) ; Dizziness ; Sore mouth ; Headaches ; Indigestion etc. Serious Side Effects of Halaven Injection : Unusual bleeding or bruising ; Black or tarry stools ; Pain or burning with urination ; Heartburn ; Skin changes ; Loss of appetite etc. Not all side effects are listed above. Eribulin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. What are the safety measures of Halaven 0.44 mg/ml ? Before Taking Halaven cancer medicine, it is important to understand all precautions or safety information associated with it. You need to remember certain points such as – Inform your health care professional if you are pregnant or may be pregnant during treatment with Halaven. This cancer medicine may be hazardous to the fetus. Use a birth control method while you are taking this medicine. Ask your doctor to help you choose a method of birth control that will work for you. If you are taking Halaven, it is advised to stop breastfeeding. This is because there are high chances that the active ingredient in the medicine can pass on to the child through breast milk. Hence, stop breastfeeding until your doctor tells you that the medicines are completely flushed out from the body, and it is safe to breast your child. You will need to have regular blood tests and check-ups during your treatment with Halaven. They’re used to track the progression of disease, and to help doctors make decisions about treatment. Tell your doctor if you have ever had any unusual or allergic reaction to Halaven cancer drug or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes or preservatives. For non-prescription products, read the label or package ingredients carefully. Alcohol can interact with Halaven. Always talk to your physician before drinking alcohol during a cancer treatment because combining alcohol and cancer medicine might have consequences on the efficacy and safety of the treatment. Halaven may interact with other medicines. Tell your doctor and pharmacist about all prescription & non-prescription medicines, vitamins and herbal supplements that you are taking at this time. Taking Eribulin together with certain medicines or products may cause serious side effects. For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule. Taking a single dose of expired medicine is unlikely to produce an adverse event. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you’ve had a medicine for a while, check the expiry date before using it. If it has expired or is damaged, return it to your pharmacist for disposal. Before using Halaven (Eribulin), tell your doctor or pharmacist about your medical history, especially if you have liver problems (including hepatitis B or C infection), diabetes, high blood pressure, kidney problems, heart or pancreas problems, or low blood potassium levels etc. What are the storage instructions for Halaven 0.44 mg/ml ? Many factors can damage your medication, including heat, air, light, and moisture. It’s important to keep in mind that where you store your medication can affect its potency and safety. Following storage instructions will be helpful in storing the drug in the best of manner. • Store Eribulin at 25°C (77°F); excursions permitted to 15°–30°C (59°–86°F). • Do not freeze. • Be sure that medicines are out of reach of any children or anyone who might misuse them. • Store the vials in their original cartons. Do not mix different medications together in the same container. This will make it difficult to identify during an emergency. • Do not store Halaven Injection in the glove compartment of a car. • Keep this injectable medicine out of bright light and sunlight.